Neuromodulation

Dr. Georgios Matis

Dr. Georgios K. Matis, MD, MSc, PhD, is the Director of Interventional Pain Management, Spasticity and Neuromodulation Unit at Hygeia Hospital in Athens, Greece. 

About Neuromodulation

Neuromodulation (NMD) is the science of gently reshaping nerve activity through precise, targeted stimulation—either electrical or chemical—at specific points within the nervous system. As a modern, evidence-based medical field, it offers a transformative pathway for patients living with chronic pain or spasticity who have found traditional treatments insufficient.

Why Choose Neuromodulation?

  • Targeted Relief: Influences nervous system communication at the source.
  • Restored Quality of Life: Enhances mobility, autonomy, and daily comfort.
  • Evidence-Based: A proven clinical alternative to systemic medications and invasive surgery.

By restoring balance to the nervous system, Neuromodulation opens the door to a life defined by dignity and functional independence rather than physical limitations.

Precision

Neuromodulation is the art of influencing specific neural circuits with millimetric accuracy. 

Precision reflects advanced imaging, refined targeting, closed-loop systems, and individualized programming.

Function

Restoring movement, autonomy, and participation in life. 

Pain relief is not the endpoint; function is. Walking again, sleeping, working, engaging. Νeuromodulation is meaningful only when it translates into lived ability.

Neuromodulation

Adaptability

Therapy that listens and responds! Unlike static treatments, neuromodulation evolves with the patient.

Feedback-driven stimulation, programming adjustments, and long-term optimization define a living therapy.

Human-Centered Care

Technology in service of dignity

At its core, neuromodulation is a dialogue between clinician, patient, and technology. Shared decision-making, empathy, and trust elevate innovation into healing.

Trust is the first step toward relief. Expertise is the second. Neuromodulation brings them together with purpose.

Media Presence

Books & Book Chapters

Newspapers & Magazines

Scientific Publications

A few things people usually ask.

What is spinal cord stimulation (SCS ) and how can it help my chronic pain?

Spinal Cord Stimulation (SCS) uses a pacemaker-like device to deliver gentle electrical signals to the spinal cord. These pulses interrupt pain signals before they reach the brain, replacing them with a soothing sensation. It is highly effective for chronic back, leg, or nerve pain that has failed other treatments, allowing patients to reduce medication and regain daily function.

Spinal cord stimulation provides a potential for long-lasting pain relief. Clinical studies show many patients maintain significant pain reduction for years after the spinal cord stimulation device is implanted. The therapy does not wear off like medications, and the system can be adjusted over time. Most patients report at least 50% reduction in their chronic pain levels.

Peripheral nerve stimulation interferes very little with daily life. Once the peripheral nerve stimulation device is implanted, you maintain control over the intensity. Most patients return to normal routines, including work, exercise, and hobbies, within a few days. The small device is discreetly placed under the skin, allowing you to stay active without the drowsiness associated with pain medications.

Within a few days! You will not have to wait months to know if peripheral nerve stimulation is working. Most patients experience relief from peripheral nerve stimulation within just a few days after the device is implanted. The procedure is minimally invasive, often performed with local anesthesia, and allows you to participate more fully in physical therapy while reducing the need for medications.

An intrathecal pain pump delivers medication directly into the fluid surrounding your spinal cord. This targeted approach is efficient, using a much smaller dose than oral medication to achieve pain relief. Because the intrathecal pain pump bypasses the digestive system, you experience fewer side effects like confusion. The programmable pump provides consistent, around-the-clock relief for severe chronic pain.

Intrathecal baclofen therapy provides powerful muscle relaxation for patients with severe spasticity. By delivering medication directly to the spinal fluid, intrathecal baclofen therapy reduces muscle stiffness and painful spasms with minimal side effects. This improved comfort enables you to participate effectively in physical therapy. A trial period confirms the therapy works for you before a permanent device is implanted.

Radiofrequency ablation (RFA) is a minimally invasive procedure using heat energy to interrupt nerves sending pain signals from arthritic joints to the brain. Radiofrequency ablation is ideal for chronic pain in the spine, neck, knees, or hips. Benefits include no surgery, immediate return to activities, and pain relief that can last from six months to two years.

Pain relief from radiofrequency ablation typically lasts between 6 months and 2 years. This makes radiofrequency ablation more durable than temporary nerve block injections. Most patients experience meaningful pain reduction within 10 days to 4 weeks. The procedure can be safely repeated if pain returns, providing an effective long-term management strategy for chronic arthritis or joint pain.